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{"type":"standard","title":"CP-122,288","displaytitle":"CP-122,288","namespace":{"id":0,"text":""},"wikibase_item":"Q20707282","titles":{"canonical":"CP-122,288","normalized":"CP-122,288","display":"CP-122,288"},"pageid":46919927,"thumbnail":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/a/a9/CP-122%2C288_Structure.svg/320px-CP-122%2C288_Structure.svg.png","width":320,"height":184},"originalimage":{"source":"https://upload.wikimedia.org/wikipedia/commons/thumb/a/a9/CP-122%2C288_Structure.svg/6906px-CP-122%2C288_Structure.svg.png","width":6906,"height":3979},"lang":"en","dir":"ltr","revision":"1195323252","tid":"cb450b06-b203-11ee-b5ae-e9ce704cd578","timestamp":"2024-01-13T11:06:26Z","description":"Chemical compound","description_source":"local","content_urls":{"desktop":{"page":"https://en.wikipedia.org/wiki/CP-122%2C288","revisions":"https://en.wikipedia.org/wiki/CP-122%2C288?action=history","edit":"https://en.wikipedia.org/wiki/CP-122%2C288?action=edit","talk":"https://en.wikipedia.org/wiki/Talk:CP-122%2C288"},"mobile":{"page":"https://en.m.wikipedia.org/wiki/CP-122%2C288","revisions":"https://en.m.wikipedia.org/wiki/Special:History/CP-122%2C288","edit":"https://en.m.wikipedia.org/wiki/CP-122%2C288?action=edit","talk":"https://en.m.wikipedia.org/wiki/Talk:CP-122%2C288"}},"extract":"CP-122,288 is a drug which acts as a potent and selective agonist for the 5-HT1B, 5-HT1D and 5-HT1F serotonin receptor subtypes. It is a derivative of the migraine medication sumatriptan, but while CP-122,288 is 40,000 times more potent than sumatriptan as an inhibitor of neurogenic inflammation and plasma protein extravasation, it is only twice as potent as a constrictor of blood vessels. In human trials, CP-122,288 was not found to be effective as a treatment for migraine, but its selectivity for neurogenic anti-inflammatory action over vasoconstriction has made it useful for research into the underlying causes of migraine.","extract_html":"
CP-122,288 is a drug which acts as a potent and selective agonist for the 5-HT1B, 5-HT1D and 5-HT1F serotonin receptor subtypes. It is a derivative of the migraine medication sumatriptan, but while CP-122,288 is 40,000 times more potent than sumatriptan as an inhibitor of neurogenic inflammation and plasma protein extravasation, it is only twice as potent as a constrictor of blood vessels. In human trials, CP-122,288 was not found to be effective as a treatment for migraine, but its selectivity for neurogenic anti-inflammatory action over vasoconstriction has made it useful for research into the underlying causes of migraine.
"}